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G J Peters Selected Research

nolatrexed (AG337)

6/2003Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines.
4/2000Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.
1/2000Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates.

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G J Peters Research Topics

Disease

60Neoplasms (Cancer)
09/2022 - 03/2000
20Colorectal Neoplasms (Colorectal Cancer)
03/2015 - 03/2000
18Colonic Neoplasms (Colon Cancer)
01/2010 - 01/2000
14Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2013 - 10/2000
13Leukemia
07/2011 - 08/2000
10Neoplasm Metastasis (Metastasis)
01/2017 - 02/2001
10Lung Neoplasms (Lung Cancer)
01/2014 - 01/2000
6Ovarian Neoplasms (Ovarian Cancer)
11/2009 - 10/2000
5Breast Neoplasms (Breast Cancer)
04/2009 - 10/2004
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2014 - 06/2002
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2008 - 08/2000
3Adenocarcinoma
01/2018 - 07/2003
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2014 - 12/2000
3Necrosis
03/2013 - 11/2000
3Carcinoma (Carcinomatosis)
10/2006 - 11/2000
2Mesothelioma
11/2017 - 11/2011
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
11/2013 - 06/2010
2Malignant Mesothelioma
11/2011 - 07/2010
2Glioblastoma (Glioblastoma Multiforme)
08/2011 - 01/2009
2Stomach Neoplasms (Stomach Cancer)
11/2008 - 03/2004
2Melanoma (Melanoma, Malignant)
10/2004 - 06/2003
2Urinary Bladder Neoplasms (Bladder Cancer)
03/2004 - 02/2004
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/2004 - 06/2003
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
06/2003 - 06/2001

Drug/Important Bio-Agent (IBA)

38GemcitabineFDA Link
01/2018 - 01/2000
28Fluorouracil (Carac)FDA LinkGeneric
08/2008 - 01/2000
18Thymidylate SynthaseIBA
11/2017 - 03/2000
16Pharmaceutical PreparationsIBA
09/2022 - 01/2000
15Proteins (Proteins, Gene)FDA Link
03/2015 - 01/2000
11EnzymesIBA
01/2014 - 06/2000
10Cisplatin (Platino)FDA LinkGeneric
01/2018 - 01/2000
9Deoxycytidine KinaseIBA
12/2011 - 03/2003
7DNA (Deoxyribonucleic Acid)IBA
09/2022 - 02/2002
7Folic Acid (Vitamin M)FDA LinkGeneric
01/2018 - 04/2000
7Pemetrexed (MTA)FDA Link
11/2017 - 01/2000
7Folic Acid AntagonistsIBA
11/2017 - 09/2000
7Thymidine PhosphorylaseIBA
03/2011 - 03/2000
7Cytarabine (Cytosar-U)FDA LinkGeneric
06/2010 - 08/2000
6Leucovorin (Folinic Acid)FDA Link
07/2006 - 08/2000
5Doxorubicin (Adriamycin)FDA LinkGeneric
02/2016 - 08/2008
5Paclitaxel (Taxol)FDA LinkGeneric
06/2009 - 01/2000
5Messenger RNA (mRNA)IBA
11/2004 - 09/2000
5DeoxycytidineIBA
10/2004 - 10/2000
4acridoneIBA
09/2022 - 05/2009
4AcridonesIBA
09/2022 - 05/2009
4Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2007 - 08/2000
3Biological ProductsIBA
09/2022 - 01/2009
3Sorafenib (BAY 43-9006)FDA Link
01/2020 - 11/2011
3PlatinumIBA
01/2018 - 01/2007
3Biomarkers (Surrogate Marker)IBA
11/2017 - 07/2010
3MicroRNAs (MicroRNA)IBA
01/2017 - 12/2011
3Calmodulin (Calcium-Dependent Activator Protein)IBA
03/2013 - 05/2009
3Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2013 - 04/2009
3Gefitinib (Iressa)FDA Link
11/2011 - 05/2004
3Irinotecan (Camptosar)FDA LinkGeneric
06/2009 - 09/2001
3ErbB Receptors (EGF Receptor)IBA
04/2009 - 05/2004
3NucleosidesIBA
01/2009 - 01/2006
3trifluridine tipiracil drug combinationIBA
11/2008 - 01/2007
3Fatty Acids (Saturated Fatty Acids)IBA
10/2004 - 02/2004
3nolatrexed (AG337)IBA
06/2003 - 01/2000
3Methotrexate (Mexate)FDA LinkGeneric
05/2002 - 08/2000
2ATP-Binding Cassette Transporters (ABC Transporters)IBA
09/2022 - 03/2008
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2020 - 11/2009
2Reduced Folate Carrier ProteinIBA
11/2017 - 10/2000
2ProdrugsIBA
07/2017 - 01/2007
2Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
01/2014 - 08/2000
22-mercaptopurineIBA
11/2013 - 06/2010
2LigandsIBA
07/2013 - 03/2013
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2013 - 11/2000
2Cytidine DeaminaseIBA
03/2012 - 06/2010
2DeoxyriboseIBA
12/2011 - 01/2008
2enzastaurinIBA
11/2011 - 09/2008
2C 1311IBA
07/2011 - 05/2009
25'-oleoyl cytarabineIBA
06/2010 - 01/2010
2CP 4126IBA
06/2010 - 01/2010
2TransferasesIBA
06/2010 - 05/2005
2Antineoplastic Agents (Antineoplastics)IBA
11/2009 - 01/2007
2ParaffinIBA
06/2009 - 03/2000
2lonafarnib (SCH 66336)IBA
06/2009 - 05/2005
2Multidrug Resistance-Associated ProteinsIBA
05/2009 - 06/2003
2Member 1 Subfamily B ATP Binding Cassette TransporterIBA
05/2009 - 06/2003
2NucleotidesIBA
01/2009 - 01/2006
2deoxycytidine deaminaseIBA
01/2009 - 02/2004
2Tyrosine Kinase InhibitorsIBA
03/2008 - 05/2004
2ThymidineIBA
01/2008 - 05/2001
2Drug CombinationsIBA
01/2007 - 08/2000
2troxacitabineIBA
01/2007 - 01/2006
2Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
01/2006 - 10/2005
2Floxuridine (FUdR)FDA LinkGeneric
10/2004 - 04/2000
2RNA (Ribonucleic Acid)IBA
07/2004 - 01/2000
2TegafurIBA
07/2003 - 08/2001
2DeoxyribonucleotidesIBA
01/2003 - 05/2001
2fas Receptor (CD95 Antigen)IBA
03/2002 - 02/2001
2AntimetabolitesIBA
09/2001 - 08/2000
2Monoclonal AntibodiesIBA
06/2000 - 01/2000
2raltitrexed (D 1694)IBA
05/2000 - 04/2000

Therapy/Procedure

17Therapeutics
09/2022 - 03/2000
14Drug Therapy (Chemotherapy)
12/2011 - 01/2000
2Combination Drug Therapy (Combination Chemotherapy)
01/2014 - 02/2004
2Aftercare (After-Treatment)
06/2002 - 05/2000